MCP-Server

raras

            io.github.rarasAI/raras
        

Gesundheitswesen Wissenschaft & Engineering Suche & Recherche Öffentlich und erreichbar MCP 2025-11-25

Was dieses MCP kann

Provides a source-grounded rare-disease knowledge graph covering diseases, phenotypes, genes, drugs, literature, clinical trials, reference centers, and evidence.

analyze_clinical_case

Analisar caso clÃnico

Caso clÃnico â doenÃ§as candidatas + literatura relevante em 1 chamada. Apenas informativo, nunca diagnÃ³stico.

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['case_description'], 'properties': {'papers_limit': {'type': 'integer', 'default': 5, 'maximum': 20, 'minimum': 1}, 'diseases_limit': {'type': 'integer', 'default': 5, 'maximum': 20, 'minimum': 1}, 'case_description': {'type': 'string', 'minLength': 20}}}

explain_relation

Explicar relaÃ§Ã£o (MedGraphRAG, raciocÃnio multi-hop)

RaciocÃnio fundamentado sobre o grafo: dada uma pergunta (ex.: "por que o gene X se associa Ã doenÃ§a Y?", "como a droga Z se relaciona a esta doenÃ§a?"), retorna caminhos de evidÃªncia multi-hop (doenÃ§aâgeneâviaâdrogaâfenÃ³tipo) com proveniÃªncia citÃ¡vel. Se nÃ£o houver caminho no grafo, recusa â nunca inventa.

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['query'], 'properties': {'query': {'type': 'string', 'minLength': 3}, 'hpo_ids': {'type': 'array', 'items': {'type': 'string', 'pattern': '^HP:\\d+$'}, 'maxItems': 20}, 'max_hops': {'anyOf': [{'type': 'number', 'const': 2}, {'type': 'number', 'const': 3}], 'default': 2}}}

Ausgabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['query', 'hasEvidence', 'summary', 'paths'], 'properties': {'paths': {'type': 'array', 'items': {'type': 'object', 'required': ['score', 'chain', 'sources'], 'properties': {'chain': {'type': 'array', 'items': {'type': 'string'}}, 'score': {'type': 'number'}, 'sources': {'type': 'array', 'items': {'type': 'string'}}}, 'additionalProperties': False}}, 'query': {'type': 'string'}, 'summary': {'type': 'object', 'required': ['diseases', 'phenotypes', 'genes', 'drugs'], 'properties': {'drugs': {'type': 'number'}, 'genes': {'type': 'number'}, 'diseases': {'type': 'number'}, 'phenotypes': {'type': 'number'}}, 'additionalProperties': False}, 'hasEvidence': {'type': 'boolean'}}, 'additionalProperties': False}

find_active_trials

Ensaios clÃnicos ativos

Trials ativos com filtro Brazil.

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'limit': {'type': 'integer', 'default': 15, 'maximum': 30, 'minimum': 1}, 'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}, 'in_brazil_only': {'type': 'boolean', 'default': False}}}

find_diseases_by_phenotypes

Buscar doenÃ§as por fenÃ³tipos

Match por IDs HPO. Use para diagnÃ³stico diferencial.

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['hpo_ids'], 'properties': {'limit': {'type': 'integer', 'default': 10, 'maximum': 30, 'minimum': 1}, 'hpo_ids': {'type': 'array', 'items': {'type': 'string', 'pattern': '^HP:\\d+$'}, 'maxItems': 20, 'minItems': 1}}}

find_papers_for_disease

Papers de uma doenÃ§a

Literatura relacionada a uma doenÃ§a via embeddings (:SEMANTIC_MATCH, fallback vetorial).

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'limit': {'type': 'integer', 'default': 10, 'maximum': 30, 'minimum': 1}, 'min_score': {'type': 'number', 'default': 0.8, 'maximum': 1, 'minimum': 0}, 'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}}}

find_phenotypically_similar

DoenÃ§as com fenÃ³tipos similares

DoenÃ§as com perfil de fenÃ³tipos HPO semelhante (simGIC prÃ©-computado, explicÃ¡vel: nÂº de fenÃ³tipos em comum). Complementa find_similar_diseases (semÃ¢ntico).

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'limit': {'type': 'integer', 'default': 10, 'maximum': 30, 'minimum': 1}, 'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}}}

Ausgabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['method', 'orphaCode', 'results'], 'properties': {'meta': {}, 'method': {'type': 'string'}, 'results': {'type': 'array', 'items': {'type': 'object', 'required': ['orphaCode', 'name', 'score', 'sharedPhenotypes', 'url'], 'properties': {'url': {'type': 'string'}, 'name': {'type': 'string'}, 'score': {'type': 'number'}, 'orphaCode': {'type': 'string'}, 'sharedPhenotypes': {'type': 'number'}}, 'additionalProperties': False}}, 'orphaCode': {'type': 'string'}}, 'additionalProperties': False}

find_reference_centers

Centros de referÃªncia

Centros por doenÃ§a e/ou UF, com CNES.

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'properties': {'limit': {'type': 'integer', 'default': 20, 'maximum': 50, 'minimum': 1}, 'state': {'type': 'string', 'maxLength': 2, 'minLength': 2}, 'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}}}

find_similar_diseases

DoenÃ§as similares

Vector similarity via embeddings SOTA.

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'limit': {'type': 'integer', 'default': 10, 'maximum': 20, 'minimum': 1}, 'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}}}

get_disease_detail

Detalhes de doenÃ§a rara

FenÃ³tipos HPO, genes, SUS, trials, descriÃ§Ã£o clÃnica em PT.

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}}}

get_evidence

ProveniÃªncia / evidÃªncias

Cross-references de autoridade (Orphanet, MONDO, OMIM, MeSH, GARD, UMLS), status de verificaÃ§Ã£o e PMIDs de uma doenÃ§a. A base da regra "nunca inventar".

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}}}

Ausgabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode', 'name', 'xrefs', 'verification', 'diseaseTwin', 'pmids', 'neverInvent'], 'properties': {'name': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}, 'pmids': {'type': 'array', 'items': {'type': 'string'}}, 'xrefs': {'type': 'object', 'required': ['orphanet', 'mondo', 'omim', 'mesh', 'gard', 'umls', 'pubtator3'], 'properties': {'gard': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}, 'mesh': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}, 'omim': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}, 'umls': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}, 'mondo': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}, 'orphanet': {'type': 'string'}, 'pubtator3': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}}, 'additionalProperties': False}, 'orphaCode': {'type': 'string'}, 'diseaseTwin': {'type': 'object', 'required': ['authoredAt', 'groundingPct'], 'properties': {'authoredAt': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}, 'groundingPct': {'anyOf': [{'type': 'number'}, {'type': 'null'}]}}, 'additionalProperties': False}, 'neverInvent': {'type': 'boolean'}, 'verification': {'type': 'object', 'required': ['status', 'checkedAt'], 'properties': {'status': {'type': 'string'}, 'checkedAt': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}}, 'additionalProperties': False}}, 'additionalProperties': False}

get_graph_stats

EstatÃsticas do grafo

Contagens e mÃ©tricas do dataset.

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'properties': {}}

get_hypotheses

HipÃ³teses de reposicionamento (co-scientist)

Candidatos a reposicionamento de fÃ¡rmacos gerados por associaÃ§Ã£o de genes (guilt-by-association): drogas que tratam outras doenÃ§as que compartilham genes com esta. HIPÃTESES para investigaÃ§Ã£o, NUNCA recomendaÃ§Ãµes clÃnicas â cada uma rastreÃ¡vel (via gene X, da doenÃ§a Y).

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}}}

Ausgabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode', 'name', 'method', 'isRecommendation', 'hypotheses'], 'properties': {'name': {'type': 'string'}, 'method': {'type': 'string'}, 'orphaCode': {'type': 'string'}, 'hypotheses': {'type': 'array', 'items': {'type': 'object', 'required': ['drug', 'viaGenes', 'sources', 'geneOverlap'], 'properties': {'drug': {'type': 'string'}, 'sources': {'type': 'array', 'items': {'type': 'object', 'required': ['name', 'orpha'], 'properties': {'name': {'type': 'string'}, 'orpha': {'type': 'string'}}, 'additionalProperties': False}}, 'viaGenes': {'type': 'array', 'items': {'type': 'string'}}, 'geneOverlap': {'type': 'number'}}, 'additionalProperties': False}}, 'isRecommendation': {'type': 'boolean'}}, 'additionalProperties': False}

get_literature_relations

RelaÃ§Ãµes mineradas da literatura (PubTator3)

RelaÃ§Ãµes tipadas extraÃdas da literatura biomÃ©dica (associate/treat/cause/inhibit/stimulate/prevent) entre a doenÃ§a e genes/fÃ¡rmacos, com nÂº de publicaÃ§Ãµes como proveniÃªncia. FiltrÃ¡vel por predicado.

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}, 'predicate': {'enum': ['associate', 'treat', 'cause', 'inhibit', 'stimulate', 'prevent', 'positive_correlation', 'negative_correlation'], 'type': 'string'}}}

Ausgabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode', 'source', 'relations'], 'properties': {'source': {'type': 'string'}, 'orphaCode': {'type': 'string'}, 'relations': {'type': 'array', 'items': {'type': 'object', 'required': ['predicate', 'partner', 'partnerType', 'publications', 'direction'], 'properties': {'partner': {'type': 'string'}, 'direction': {'type': 'string'}, 'predicate': {'type': 'string'}, 'partnerType': {'type': 'string'}, 'publications': {'type': 'number'}}, 'additionalProperties': False}}}, 'additionalProperties': False}

get_recent_updates

Disease Twins atualizados recentemente

DoenÃ§as cujo gÃªmeo digital ganhou evidÃªncia nova (autoria, PubTator3, Open Targets, verificaÃ§Ã£o) nos Ãºltimos N dias. FaÃ§a polling para acompanhar mudanÃ§as (substituto stateless de subscriptions).

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'properties': {'days': {'type': 'integer', 'default': 7, 'maximum': 90, 'minimum': 1}, 'limit': {'type': 'integer', 'default': 20, 'maximum': 100, 'minimum': 1}}}

Ausgabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['sinceDays', 'updates'], 'properties': {'updates': {'type': 'array', 'items': {'type': 'object', 'required': ['orphaCode', 'name', 'lastUpdated', 'sources', 'resource'], 'properties': {'name': {'type': 'string'}, 'sources': {'type': 'array', 'items': {'type': 'string'}}, 'resource': {'type': 'string'}, 'orphaCode': {'type': 'string'}, 'lastUpdated': {'type': 'string'}}, 'additionalProperties': False}}, 'sinceDays': {'type': 'number'}}, 'additionalProperties': False}

get_research_log

DiÃ¡rio de pesquisa do Disease Twin

Registro cronolÃ³gico do que o agente autÃ´nomo fez por esta doenÃ§a: autoria, mineraÃ§Ã£o de literatura, evidÃªncia genÃ©tica, verificaÃ§Ã£o, prospecÃ§Ã£o de fontes, recomputaÃ§Ã£o de relaÃ§Ãµes. Prova de que o gÃªmeo digital estuda a doenÃ§a continuamente.

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}}}

Ausgabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode', 'name', 'events'], 'properties': {'name': {'type': 'string'}, 'events': {'type': 'array', 'items': {'type': 'object', 'required': ['date', 'type', 'title', 'detail'], 'properties': {'date': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}, 'type': {'type': 'string'}, 'title': {'type': 'string'}, 'detail': {'type': 'string'}}, 'additionalProperties': False}}, 'orphaCode': {'type': 'string'}}, 'additionalProperties': False}

get_schema

Esquema do grafo

Node labels, relationship types e property keys do grafo. Use antes de cypher_query.

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'properties': {}}

get_sus_coverage

Cobertura SUS

CEAF, SIGTAP, PNTN, nÃvel de integraÃ§Ã£o.

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['orphaCode'], 'properties': {'orphaCode': {'type': 'string', 'pattern': '^\\d+$'}}}

search_diseases

Buscar doenÃ§as raras

Full-text search em 10.468 doenÃ§as raras. Suporta filtros SUS/trials.

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['query'], 'properties': {'limit': {'type': 'integer', 'default': 10, 'maximum': 50, 'minimum': 1}, 'query': {'type': 'string', 'minLength': 2}, 'filter_has_sus_coverage': {'type': 'boolean'}, 'filter_has_active_trials': {'type': 'boolean'}}}

search_papers_semantic

Busca semÃ¢ntica de papers

Busca vetorial sobre 424k papers do PubMed. Use caso clÃnico, pergunta ou conjunto de sintomas.

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['query'], 'properties': {'limit': {'type': 'integer', 'default': 10, 'maximum': 30, 'minimum': 1}, 'query': {'type': 'string', 'minLength': 3}, 'min_score': {'type': 'number', 'default': 0.8, 'maximum': 1, 'minimum': 0}}}

search_phenotypes

Buscar fenÃ³tipos HPO

Lookup HPO em PT-BR (encoder Araras-HPO-Brasil + lÃ©xico leigo) ou EN (vocabulÃ¡rio HPO). Retorna IDs HP: com estado de asserÃ§Ã£o: termo NEGADO ("nunca desmaiei") NÃO vira fenÃ³tipo. Outros idiomas nÃ£o sÃ£o cobertos. Limite de taxa: use poucas chamadas por minuto (429 = espere).

Nur Lesen

Eingabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['query'], 'properties': {'limit': {'type': 'integer', 'default': 15, 'maximum': 50, 'minimum': 1}, 'query': {'type': 'string', 'minLength': 2}}}

Ausgabeschema

{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['query', 'assertion', 'results'], 'properties': {'meta': {}, 'note': {'type': 'string'}, 'query': {'type': 'string'}, 'results': {'type': 'array', 'items': {'type': 'object', 'required': ['hpoId', 'name', 'namePt', 'match', 'via', 'similarity'], 'properties': {'via': {'type': 'string'}, 'name': {'type': 'string'}, 'hpoId': {'type': 'string'}, 'match': {'enum': ['exact', 'approximate'], 'type': 'string'}, 'namePt': {'anyOf': [{'type': 'string'}, {'type': 'null'}]}, 'similarity': {'anyOf': [{'type': 'number'}, {'type': 'null'}]}}, 'additionalProperties': False}}, 'assertion': {'enum': ['PRESENT', 'NEGATED'], 'type': 'string'}, 'languages': {'type': 'string'}}, 'additionalProperties': False}

Geändert

                            search_phenotypes
                        

23. September 2026 02:47

Geändert

                            find_phenotypically_similar
                        

21. September 2026 02:54

Hinzugefügt

                            get_evidence
                        

17. September 2026 12:49

Hinzugefügt

                            get_recent_updates
                        

17. September 2026 12:49

Hinzugefügt

                            get_research_log
                        

17. September 2026 12:49

Hinzugefügt

                            get_hypotheses
                        

17. September 2026 12:49

Hinzugefügt

                            get_literature_relations
                        

17. September 2026 12:49

Hinzugefügt

                            explain_relation
                        

17. September 2026 12:49

Hinzugefügt

                            get_schema
                        

17. September 2026 12:49

Hinzugefügt

                            analyze_clinical_case
                        

17. September 2026 12:49

Hinzugefügt

                            find_papers_for_disease
                        

17. September 2026 12:49

Hinzugefügt

                            search_papers_semantic
                        

17. September 2026 12:49

Hinzugefügt

                            get_graph_stats
                        

17. September 2026 12:49

Hinzugefügt

                            find_phenotypically_similar
                        

17. September 2026 12:49

Hinzugefügt

                            find_similar_diseases
                        

17. September 2026 12:49

Hinzugefügt

                            find_active_trials
                        

17. September 2026 12:49

Hinzugefügt

                            find_reference_centers
                        

17. September 2026 12:49

Hinzugefügt

                            get_sus_coverage
                        

17. September 2026 12:49

Hinzugefügt

                            search_phenotypes
                        

17. September 2026 12:49

Hinzugefügt

                            find_diseases_by_phenotypes
                        

17. September 2026 12:49

Hinzugefügt

                            get_disease_detail
                        

17. September 2026 12:49

Hinzugefügt

                            search_diseases
                        

17. September 2026 12:49

Serverdetails

Version

0.2.0

Transport

Streamable HTTP

Tools

Latenz

3436 ms

Letzter Scan

1. October 2026 02:48

Erstmals gesehen

13. September 2026 02:21

Endpunkt

https://raras.org/api/mcp

Letzte Scans

Erfolgreich

1. October 2026 02:48

Erfolgreich

29. September 2026 02:56

Erfolgreich

27. September 2026 02:47

Erfolgreich

25. September 2026 02:55

Erfolgreich

23. September 2026 02:47

Erfolgreich

21. September 2026 02:54

Erfolgreich

19. September 2026 02:45

Erfolgreich

17. September 2026 12:49

raras

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