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Oliver's mTOR Atlas

io.github.open-mtor-atlas/mtor-atlas
Science et ingénierie Recherche et exploration Public et accessible MCP 2025-11-25

Ce que fait ce MCP

Provides an evidence-labelled knowledge base of mTOR entities, pathway relations, studies, contradictions, and open research questions.

Capacités

Outils

11 outils
atlas_about
About the Atlas
Dataset version, corpus snapshot date, counts, evidence-code legend and how to cite the dataset.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', 'properties': {}}
evidence_between
Evidence between two entities
Direct curated relations between two entities (either direction) with full cards for the supporting and conflicting studies. Answers questions such as "what is the evidence that A acts on B?".
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['a', 'b'], 'properties': {'a': {'type': 'string'}, 'b': {'type': 'string'}}}
find_contradictions
Find contested claims
Relations the Atlas marks as contested or that carry conflicting studies, with both sides of the evidence. Optionally limited to one entity.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'properties': {'limit': {'type': 'integer', 'default': 20, 'maximum': 50, 'minimum': 1}, 'entity': {'type': 'string'}}}
find_relations
Find pathway relations
Signed, evidence-linked pathway relations (claims such as "Rheb activates mTORC1"). Filter by an entity on either end, by source/target, effect, contested status or minimum strength of the best supporting evidence.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'properties': {'limit': {'type': 'integer', 'default': 20, 'maximum': 50, 'minimum': 1}, 'effect': {'enum': ['activates', 'inhibits', 'binds', 'recruits', 'required-for', 'context-dependent', 'no-effect'], 'type': 'string'}, 'entity': {'type': 'string', 'description': 'Entity on either end of the relation'}, 'offset': {'type': 'integer', 'default': 0, 'maximum': 9007199254740991, 'minimum': 0, 'description': 'For the next page: pass next_offset from the previous answer.'}, 'source': {'type': 'string'}, 'target': {'type': 'string'}, 'contested_only': {'type': 'boolean', 'description': 'Only relations marked contested or with conflicting studies'}, 'strongest_at_least': {'enum': ['S', 'H', 'A', 'M', 'R', 'PP', 'RT'], 'type': 'string', 'description': 'Keep relations whose best supporting study is at least this code in the order S > H > A > M'}}}
get_entity
Get one entity
One entity (gene/protein, complex, drug, disease, process...) with its linked studies as short cards (first studies_limit) and every pathway relation it takes part in as a one-line claim. Accepts an id, a name or a synonym.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['entity'], 'properties': {'entity': {'type': 'string', 'description': 'e.g. "mTORC1", "Rheb", "rapamycin"'}, 'studies_limit': {'type': 'integer', 'default': 25, 'maximum': 50, 'minimum': 0}}}
get_question
Get one question
One open or frontier question by ID (e.g. "H1", "F2"): the gap, what changed, what is still open, how it could be tested, linked studies.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['id'], 'properties': {'id': {'type': 'string'}}}
get_relation
Get one relation
One pathway relation by ID (e.g. "RHEB-MTORC1"): mechanism, boundary conditions, confidence, supporting and conflicting studies.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['id'], 'properties': {'id': {'type': 'string'}}}
get_study
Get one study
Full record for one study by Atlas ID (e.g. "SAB1994"): abstract excerpt, extracted findings, linked entities, the relations it supports or contradicts, related open questions.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['sid'], 'properties': {'sid': {'type': 'string', 'description': 'Atlas study ID, e.g. "SAB1994"'}}}
list_questions
List open questions
The Atlas's open questions (evidence gaps with testable hypotheses) and frontier questions.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'properties': {'kind': {'enum': ['open-question', 'frontier'], 'type': 'string'}}}
search_entities
Search entities
Find genes/proteins, complexes, drugs, diseases, processes, nutrients and outcomes by name or synonym.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'required': ['query'], 'properties': {'type': {'type': 'string', 'description': 'Optional type filter, e.g. "Drug", "Gene/Protein", "Disease"'}, 'limit': {'type': 'integer', 'default': 20, 'maximum': 100, 'minimum': 1}, 'query': {'type': 'string', 'description': 'Name or synonym, e.g. "raptor", "sirolimus"'}}}
search_studies
Search studies
Search the curated studies by keywords (title, finding, authors, journal, model system), optionally filtered by evidence code, a linked entity (gene, drug, disease...) and year range. Returns summary records with evidence codes and URLs.
Lecture seule Idempotent
Schéma d’entrée 
{'type': 'object', '$schema': 'http://json-schema.org/draft-07/schema#', 'properties': {'limit': {'type': 'integer', 'default': 20, 'maximum': 50, 'minimum': 1}, 'query': {'type': 'string', 'description': 'Keywords, e.g. "rapamycin lifespan mice". Omit to list by filters only.'}, 'entity': {'type': 'string', 'description': 'Only studies linked to this entity (name, synonym or id), e.g. "Rheb".'}, 'offset': {'type': 'integer', 'default': 0, 'maximum': 9007199254740991, 'minimum': 0, 'description': 'For the next page: pass next_offset from the previous answer.'}, 'year_to': {'type': 'integer', 'maximum': 9007199254740991, 'minimum': -9007199254740991}, 'year_from': {'type': 'integer', 'maximum': 9007199254740991, 'minimum': -9007199254740991}, 'evidence_code': {'type': 'array', 'items': {'enum': ['S', 'H', 'A', 'M', 'R', 'PP', 'RT'], 'type': 'string'}, 'description': 'Keep only these evidence codes, e.g. ["H","S"] for human evidence.'}}}
Historique

Modifications récentes des outils

Ajouté
get_question
2 October 2026 02:40
Ajouté
list_questions
2 October 2026 02:40
Ajouté
find_contradictions
2 October 2026 02:40
Ajouté
evidence_between
2 October 2026 02:40
Ajouté
get_relation
2 October 2026 02:40
Ajouté
find_relations
2 October 2026 02:40
Ajouté
get_entity
2 October 2026 02:40
Ajouté
search_entities
2 October 2026 02:40
Ajouté
get_study
2 October 2026 02:40
Ajouté
search_studies
2 October 2026 02:40
Ajouté
atlas_about
2 October 2026 02:40
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